Possible complications of hepatitis B

        In the past, the hepatitis B virus (HBV) has a "characteristics of the liver", only in the human body of the liver cells to reproduce. In recent years, with the development of detective methods, found in other tissues and organs outside the liver HBv can also invade the human body, and replicate in the corresponding tissue cells, DNA genes and virus integrated into liver cells to cause a series of pathological changes and the occurrence of multi system and multi organ disease. Common there:

        (1) arthritis: the affected joints are often single, can also be multiple, symmetrical, with the elbow, wrist, knee joint for more than see, the pain is not severe, quite similar to migratory rheumatoid arthritis.

        (2): the most common skin lesions with urticaria, followed by erythema, plaque mound diagnosis, angioedema, occasional erythematous nodules and scarlatiniform rash.

Most of the above lesions in the early days to a few weeks before the onset of acute hepatitis symptoms, that is, the incubation period of acute viral hepatitis or early stage of disease. More common in young people.

        (3): cardiovascular diseases such as myocarditis, pericarditis, polyarteritis nodosa etc.. The first two may be caused by the direct invasion of the virus. The latter is caused by immune complex deposition in small vessel wall.

        (4) renal disease: more common. The early asymptomatic proteinuria and hematuria, even granule tube type, disease and complex and refractory, gradually developed into renal insufficiency. There are also self-healing cases.

        (5) blood system disease: mainly aplastic anemia and hemolytic anemia. More common in children and youth.

        (6) the digestive system disease: early gastrointestinal mucosa inflammatory changes, the abdominal discomfort, nausea, vomiting and other symptoms. Patients with acute viral hepatitis because of jejunal disaccharidase and alkaline phosphatase (ALP) activity decreased intake of disaccharide intolerance and often have diarrhea. Some patients because of serious damage to liver or biliary obstruction can not fully excretion of bile salts and steatorrhea.

        (7) acute pancreatitis: see more acute edema pancreatitis, mainly in patients with severe hepatitis, the reason is unknown. The pancreatic involvement of non severe acute hepatitis is not obvious, only a short and mild diabetes.

        (8) nervous system lesions: nervous system involvement in cranial nerve involvement is common, can smell, taste disorder, hearing loss, vestibular dysfunction, sensory dysfunction and facial trigeminal nerve and glossopharyngeal nerve involvement.

In rare cases can occur aseptic meningitis, encephalitis, peripheral neuritis and GuillainBarre syndrome etc.. Acute stage patients often have short mental changes, such as irritability, irritability, insomnia, dreaminess, some psychiatric symptoms during the recovery period after a period of time is still sustainable. Very few people appear manic or depressive height.

        (9) vitamin deficiency: chronic hepatitis with vitamin D deficiency, and the lack of secondary calcium and phosphorus, leading to bone softening, bone pain, and even stomach% of chronic hepatitis, cirrhosis and hepatocellular carcinoma. Often suffer from vitamin A deficiency, dark adaptation disorder or flashing light as the recovery of visual acuity disorder. The duration of acute hepatitis can also occur.

        (10) the changes of thyroid function: mainly occur in patients with thyroid dysfunction, serum protein binding iodine, basal metabolic rate increased, the reduction of iodine absorption. By the acute hepatitis A.

        (11) gren syndrome: including dry keratitis, dry mouth and a connective tissue disease (most common is rheumatoid arthritis or systemic lupus erythematosus patients with salivary gland and / or lacrimal gland can be enlarged. More common in 65 to 40 year old female, the ratio of male and female is 1:9, rare in children. )

        (12): the other was seen in renal tubular acidosis, interstitial pneumonia, even acute polymyositis and severe respiratory alkalosis caused by pleural effusion, etc..