They can cause fatty liver.

      (1) dietary factors: first, long-term malnutrition, hunger or long-term consumption of high fat, high cholesterol (such as fat, egg yolk, butter, chocolate, etc.) is an important reason for the formation of fatty liver. In addition to emphasize that many patients once infected liver disease or other chronic diseases, quiescent, uncontrolled to increase nutrition and high calorie diet, or long-term continuous intravenous injection of high concentration of glucose, resulting in excess nutrients, will eventually lead to fatty liver.

      (2) a large number of long-term alcohol consumption: under the effect of alcohol can also make the liver fat metabolism disorders, the accumulation of fat cells, the occurrence of chronic alcoholic fatty liver".

      (3) obesity: about half of the obese patients can be seen with mild fatty liver: in patients with severe obesity, the incidence of fatty liver can be as high as 60%-90%. Obviously obese patients have obvious tendency of fatty liver.

      (4) drug or chemical poison: such as steroid hormone, growth hormone, salicylic acid preparation (such as aspirin), certain sedative hypnotics, industrial or laboratory commonly used alcohol, benzene, arsenic, antimony, carbon tetrachloride, iodoform are easy to induce fatty liver.

      (5) infection: such as tuberculosis, chronic ulcerative colitis, chronic bronchitis, chronic liver, gallbladder, kidney disease can often be accompanied by fatty liver.

      (6) endocrine diseases: diabetes, pituitary gland and hyperthyroidism, especially in patients with diabetes, the incidence of fatty liver was 20%-80% (average 50%), and fatty liver patients with diabetes were also accounted for 4%-46% (average 25%).

      (7) chronic hypoxia, such as severe anemia, cardiovascular and respiratory diseases and high altitude, altitude operations, often because of severe hypoxia, affect the liver's fat metabolism function, and thus the occurrence of fatty liver.

      (8) other: people who do not love sports, who work for a long time, may also have fatty liver. Fatty liver can also be directly through the development of inflammation of the liver fibrosis; liver fibrosis can also occur after the disappearance of fat. HSC plays a major role in the pathogenesis of fatty liver fibrosis and other chronic liver diseases. Ethanol, acetaldehyde, lipids, fatty acids can directly activate HSC, but also can stimulate the proliferation of HSC by stimulating Kupffer cells. In addition, lipid peroxidation may also stimulate the activation and proliferation of HSC. In comparison, there are more understanding of the pathogenesis of NASH, ALD may have its own characteristics, its pathogenesis is still to be further studied.

Prevention and treatment of fatty liver is the most important to identify and remove the cause of the disease. By drinking and gradually lose weight (short time weight loss may promote liver cell necrosis), the treatment of diabetes, lipid metabolism disorder and avoid liver toxic drug treatment, most patients with fatty liver can be reversed. Drug treatment is mainly to improve the body's antioxidant capacity such as antioxidant, inhibiting fatty acid beta oxidation, inhibition of CYP II E1 activation, anti cytokines such as TNF and soluble receptors, protect the liver cells ATP storage and use of anti endotoxin agent. However, some of the risk factors for NASH patients are not known, the role of the above treatment is still difficult to determine, especially the lack of efficacy of the corresponding indicators to judge, to strengthen the research.