Responsive-img

Contact

Address:

Weifang City mountain gorge Zuo Shan Street North Song Xing Lu

zip code: 261300

contact: Li Germany

Tel:0536-7759188

18660676677

13853627931

Fax: 0536-7752696

Cirrhosis knowledge

Four stages of the development of liver cirrhosis

Date:2016-10-18 16:11:11 FROM: Browsing times:
        Release date: 16:11:11 2016-10-18 source: browse times: 0
        (a) the early stage of ascites
        At this time there is no ascites in patients with cirrhosis, there is no systemic circulation of the expansion and filling of the artery, but excessive intake of sodium will cause water and sodium retention, that is, the kidney of the treatment of sodium has been impaired. This is due to the increase in liver function and portal pressure through the nerve reflex directly affect the kidneys to the treatment of sodium salt, but this is the limit of sodium water retention.
        (two) reactive ascites
        In this period, the renal sodium water retention increased obviously, and the total blood volume expansion, and the peripheral artery dilatation to reduce the vascular resistance. The expansion of the peripheral artery is due to the release of a large number of various kinds of vascular substances, which lead to the expansion of internal organs and circulation. Following, according to the peripheral artery hypothesis and the formation of ascites.
        (three) refractory ascites
        In this period, patients with severe liver disease, obvious sodium water retention, is not sensitive to diuretic therapy, hemodynamic instability. Plasma renin angiotensin aldosterone system and sympathetic nervous system activity, peripheral blood vessels to reduce the reactivity of vasoactive substances. However, the renal vessels are very sensitive to the blood vessels, and the kidney to the sodium re absorption is further increased and the excretion decreased, and the effect of the diuretic and natriuretic factor.
        (four) the period of liver and kidney syndrome
        This period occurs in patients with refractory ascites in patients with cirrhosis. As a result of further peripheral arterial dilation and the emergence of low blood pressure, the machine as the maintenance of effective circulating capacity, resulting in increased vascular contractile substance synthesis, especially the increase in plasma endothelin levels. Due to the high sensitivity of the renal vessels to the contractile substance, the selective renal perfusion, severe sodium water retention and renal failure were the result.

 

Previous:
Next: